Evaluation of bile acid and deranged liver function test in obstetrics cholestasis in pregnancy in fetal and perinatal outcome

Background: Pregnancy-related intrahepatic cholestasis is most prevalent hepatic disorder intense pruritus that affects the entire body including palm and sole. It typically detected during second or third trimester. Pruritus frequently exacerbates at night, marked on palms soles of feet hands. Aim this study was to evaluate bile acid deranged liver function test in obstetrics pregnancy determine maternal fetal outcomes. Methods: This prospective case series conducted Department Obstetrics Gynaecology, Muzaffarnagar Medical College. The present 50 women, who were selected from outpatient department antenatal care tertiary care, taken written permission before study. medical records all women with delivered between December 2021and August 2022. Results: Subjects IHCP has mean age 30.11±5.03 year, found SGOT 40% 100-200 SGPT 44 % I (0-100) range total bilirubin levels 33 patients. In LSCS due 24% distress, 36% MSL, 16% IUGR, 14% preterm. Participants have 22% birth weight <2.5kg 39 (78%) are under >2.5kg babies patients 24 underwent distress preterm delivery 6 got IUD . no stillborn 12% meconium. Conclusions: causes impaired LFT raised serum acids. Maternal morbidity increased terms rates discomfort pruritus.